Our first official serial killer, Dr H H Holmes, went even further in 1893. He built a fully equipped hotel right near the grounds of the World's Columbian Exposition in Chicago. Unfortunately, his taste ran to women, but you can't have everything. He had 27 confirmed victims but up to 200 actual (thanks Wikipedia):
"Holmes purchased a lot across from the drugstore, where he built his three-story, block-long "Castle"—as it was dubbed by those in the neighborhood. It was opened as a hotel for the World's Columbian Exposition in 1893, with part of the structure used as commercial space. The ground floor of the Castle contained Holmes's own relocated drugstore and various shops, while the upper two floors contained his personal office and a maze of over one hundred windowless rooms with doorways opening to brick walls, oddly angled hallways, stairways to nowhere, doors openable only from the outside, and a host of other strange and labyrinthine constructions. Holmes repeatedly changed builders during the construction of the Castle so only he fully understood the design of the house, thus decreasing the chance of being reported to the police.
After the completion of the hotel, Holmes selected mostly female victims from among his employees (many of whom were required as a condition of employment to take out life insurance policies for which Holmes would pay the premiums but also be the beneficiary), lovers and hotel guests, torturing and killing them. Some were locked in soundproof bedrooms fitted with gas lines that let him asphyxiate them at any time. Some victims were locked in a huge soundproof bank vault near his office where they were left to suffocate. The victims' bodies were dropped by secret chute to the basement, where some were meticulously dissected, stripped of flesh, crafted into skeleton models, and then sold to medical schools. Holmes also cremated some of the bodies or placed them in lime pits for destruction. Holmes had two giant furnaces as well as pits of acid, bottles of various poisons, and even a stretching rack. Through the connections he had gained in medical school, he sold skeletons and organs with little difficulty."
I've been by the site. It's now a US Post Office. Bet no other buyer would touch the property.