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A Boeing 737 airliner with 104 passengers on board from Cuba's state airline Cubana de Aviacion has crashed and exploded near Jose Marti International Airport in Havana.
The plane came down shortly after take-off, Prensa Latina news agency said.
Radio Habana Cuba said it was an internal flight from the Cuban capital to Holguin, in the east of the island.
Witnesses told AFP news agency they could see a thick column of smoke near the airport.